Ulcerative Colitis At A Glance
- Ulcerative colitis is an inflammation of the large intestine (colon).
- The cause of ulcerative colitis is unknown.
- Intermittent rectal bleeding, crampy abdominal pain and diarrhea often are symptoms of ulcerative colitis.
- The diagnosis of ulcerative colitis can be made with a barium enema, but direct visualization (sigmoidoscopy or colonoscopy) is the most accurate means of diagnosis.
- Long-standing ulcerative colitis is a risk factor for colon cancer.
- Treatment of ulcerative colitis may involve both medications and surgery.
- Ulcerative colitis also can cause inflammation in joints, spine, skin, eyes, and the liver and its bile ducts.
در متون ومنابع خارجی کولیت بطور خیلی خلاصه اینگونه تعریف شده است
کولیت اولسروز در یک نگاه :
کولیت اولسروز نوعی التهاب در روده بزرگ است
عامل ان ناشناخته است
خونروی متناوب کرامپ ودرد شکمی واسهال اغلب از نشانه های ان هستند
روش تشخیص بیماری با انمای باریوم ممکن است اما مشاهده مستقیم ( سیگموئید سکوپی وکولونسکوپی )مهمترین راه شناخت بیماری است
طول کشیدن مدت بیماری میتواند فاکتوری برای ابتلای کولون به کانسر باشد
معالجه بیماری با دارو درمانی وجراحی انجام میشود
التهاب ممکن است زانوها مهره های کمر پوست وچشمها وکبد ومجاری
صفراوی را هم درگیر کند
Ulcerative colitis is a chronic inflammation of the large intestine (colon). The colon is the part of the digestive system where waste material is stored. The rectum is the end of the colon adjacent to the anus. In patients with ulcerative colitis, ulcers and inflammation of the inner lining of the colon lead to symptoms of abdominal pain, diarrhea, and rectal bleeding.
Ulcerative colitis is closely related to another condition of inflammation of the intestines called Crohn"s disease. Together, they are frequently referred to as inflammatory bowel disease (IBD). Ulcerative colitis and Crohn"s diseases are chronic conditions that can last years to decades. They affect approximately 500,000 to 2 million people In the United States. Men and women are affected equally. They most commonly begin during dolescence and early adulthood, but they also can begin during childhood and later in life.
It is found worldwide, but is most common in the United States, England, and northern Europe. It is especially common in people of Jewish descent. Ulcerative colitis is rarely seen in Eastern Europe, Asia, and South America, and is rare in the black population. For unknown reasons, an increased frequency of this condition has been recently observed in developing nations.
What Causes Ulcerative Colitis?
Ulcerative colitis and Crohn"s disease are caused by abnormal activation of the immune system in the intestines. The immune system is composed of immune cells and the proteins that these cells produce. These cells and proteins serve to defend the body against harmful bacteria, viruses, fungi, and other foreign invaders. Activation of the immune system causes inflammation within the tissues where the activation occurs. (Inflammation is, in fact, an important mechanism of defense used by the immune system.) Normally, the immune system is activated only when the body is exposed to harmful invaders. In patients with Crohn"s disease and ulcerative colitis, however, the immune system is abnormally and chronically activated in the absence of any known invader. The continued abnormal activation of the immune systems causes chronic inflammation and ulceration. The susceptibility to abnormal activation of the immune system is genetically inherited. First degree relatives (brothers, sisters, children, and parents) of patients with IBD are thus more likely to develop these diseases.